Symptoms of Mesothelioma may include:

Coughing
Shortness of breath or difficulty breathing
Difficulty Sleeping
Weight Loss
Pain in chest and abdomen
Fluid in the chest
Usually, difficulty breathing and a lingering cough bring patients into the doctor for evaluation. This occurs because tumors of the mesothelium make if hard for the lungs to expand smoothly. Large tumors, or tumors that spread to the chest wall can cause chest pain. When fluid builds up in the pleura, breathing can be even more difficult while lying down, making it hard to sleep. The spread of cancerous cells takes a toll on your body, causing weakness, extreme fatigue. Changes in your body’s ability to absorb nutrients as a result of invasion into the abdomen can cause weight loss. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.Depending on the type of mesothelioma, slightly different symptoms can occur. Peritoneal disease has an effect on the intestines, liver and other structures in the abdominal cavity. As fluid builds up, the abdomen can become very expanded. Because the liver plays a big part in manufacturing the substances needed to control bleeding, there is often a change in your ability to make blood clots. Weight loss occurs for several reasons, and is more dramatic in this form of the disease. The pleural form of mesothelioma can also cause damage to the upper airway. Swallowing can become difficult, and voice changes can occur if the larynx is affected.